Article
Intramucosal carcinomas of the stomach: phenotypic expression and loss of heterozygosity at microsatellites linked to the APC gene.
Pathology, research and practice - 1 Jan 1998
Wu L B, Kushima R, Borchard F, Molsberger G, Hattori T
Abstract excerpt
Evaluation of the role of somatic genetic alterations in cancer development is best performed by examining small tumors in the earlier stages of carcinogenesis. We examined the relationship between allelic deletions of 4 microsatellites linked to the adenomatous polyposis coli (APC) gene and diff...
Topics
- Adenocarcinoma, Mucinous
- Adult
- Aged
- Aged, 80 and over
- Chromosomes, Human, Pair 5
- DNA, Neoplasm
- Female
- Gastric Mucosa
- Gene Deletion
- Genes, APC
- Humans
- Immunoenzyme Techniques
- Loss of Heterozygosity
- Male
- Microsatellite Repeats
- Middle Aged
- Mucins
- Phenotype
