Article
Splice variants of the nuclear dot-associated Sp100 protein contain homologies to HMG-1 and a human nuclear phosphoprotein-box motif.
Journal of cell science - 1 Mar 1999
Guldner H H, Szostecki C, Schröder P, Matschl U, Jensen K, Lüders C, Will H, Sternsdorf T
Abstract excerpt
Sp100 and PML are interferon-inducible proteins associated with a new class of nuclear domains (known as nuclear dots or PML bodies) which play a role in tumorigenesis, virus infections, and autoimmunity. While PML is extensively alternatively spliced, only two splice variants are known for Sp100. Here we describe the identification and characterization of several Sp100 splice variant proteins and support their...
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