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Article

Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl- currents.

The American journal of physiology - 1 Feb 1999

Vanoye C G, Castro A F, Pourcher T, Reuss L, Altenberg G A

Abstract excerpt

Several proteins belonging to the ATP-binding cassette superfamily can affect ion channel function. These include the cystic fibrosis transmembrane conductance regulator, the sulfonylurea receptor, and the multidrug resistance protein P-glycoprotein (MDR1). We measured whole cell swelling-activated Cl- currents (ICl,swell) in parental cells and cells expressing wild-type MDR1 or a phosphorylation-defective mutant...

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Identifiers

PMID: 9950764
DOI: 10.1152/ajpcell.1999.276.2.C370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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