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Article

p53 immunoreactivity and single-strand conformational polymorphism analysis often fail to predict p53 mutational status.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 1999

Tolbert D M, Noffsinger A E, Miller M A, DeVoe G W, Stemmermann G N, Macdonald J S, Fenoglio-Preiser C M

Abstract excerpt

The intent of this study was to investigate the ability of p53 expression and single-strand conformational polymorphism analysis (SSCP) to predict p53 mutational status in archival, paraffin-embedded tissues of gastric cancer. We evaluated paraffin-embedded tissues from 78 patients with advanced gastric cancer. The mutational status of the p53 gene (exons 5-9) was examined by SSCP analysis and by direct...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 9950163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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