Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.

Abstract excerpt

Hypertensive nephrosclerosis is a leading cause of end-stage renal disease; therefore, strategies to prevent the development of renal disease require close study. Here it is demonstrated that transient treatment of prepubescent rats with angiotensin inhibitors attenuated their susceptibility to the development of hypertensive nephrosclerosis after maturation. Stroke-prone spontaneously hypertensive Izumo strain...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Angiotensin-Converting Enzyme Inhibitors
• Share to Angiotensin Receptor Antagonists