Article
Triplet repeat variability in the signal peptide sequence of the Xmrk receptor tyrosine kinase gene in Xiphophorus fish.
Gene - 11 Dec 1998
Schartl M, Wilde B, Hornung U
Abstract excerpt
Trinucleotide repeats in several human genes have been found to undergo spontaneous variation in repeat numbers in succeeding generations. Expansion of the repeat beyond a certain length causes specific pathological disorders. So far, a naturally occurring triplet repeat instability of transcribe...
Topics
- Alleles
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Cyprinodontiformes
- Female
- Fish Proteins
- Genes
- Genetic Variation
- Heterozygote
- Homozygote
- Male
- Molecular Sequence Data
- Mutation
- Protein Sorting Signals
- Receptor Protein-Tyrosine Kinases
- Species Specificity
- Trinucleotide Repeats