Article
Are only repeated triplets guilty?
Journal of theoretical biology - 7 Sept 1998
De Fonzo V, Bersani E, Aluffi-Pentini F, Castrignanò T, Parisi V
Abstract excerpt
It is well known that in some places of the human genome one finds a variable number of tandem repeats of trinucleotides; it is now commonly acknowledged that in many cases an excessive expansion of such a number is the cause of nervous system diseases. Moreover there exist cases of genetic disor...
Topics
- Base Sequence
- Genetic Diseases, Inborn
- Humans
- Molecular Sequence Data
- Mutation
- Neurodegenerative Diseases
- Point Mutation
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid
- Trinucleotide Repeats