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Article

Instability in the transmission of the myotonic dystrophy CTG repeat in human oocytes and preimplantation embryos.

Fertility and sterility - 1 Jul 2006

Dean Nicola L, Tan Seang Lin, Ao Asangla

Abstract excerpt

OBJECTIVE: To elucidate the timing and variability of CTG repeat expansion within the human dystrophia myotonica protein kinase (DMPK) gene in early development. DESIGN: Triplet-primed polymerase chain reaction was used to amplify the expanded CTG repeat in oocytes and embryos obtained from myotonic dystrophy 1 (DM1) patients, and a heminested polymerase chain reaction approach was used to amplify the normal CTG...

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Source

Identifiers

PMID: 16716318
DOI: 10.1016/j.fertnstert.2005.12.025

Genes

DMPK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Instability in the transmission of the myotonic dystrophy CTG repeat in human oocytes and preimplantation embryos.PMID 16716318Read ↗

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