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Article

Epilepsy and obesity in serotonin 5-HT2C receptor mutant mice.

Annals of the New York Academy of Sciences - 15 Dec 1998

Heisler L K, Chu H M, Tecott L H

Abstract excerpt

Serotonin 5-HT2C receptor null mutant mice were generated to assess the contribution of this receptor to the actions of serotonin. Mutant mice displayed both an epilepsy and obesity phenotype. The epilepsy syndrome was characterized by spontaneous seizures, lowered seizure threshold, enhanced sei...

Topics

Animals
Brain
Epilepsy
Feeding Behavior
Mice
Mice, Mutant Strains
Mice, Neurologic Mutants
Nerve Net
Obesity
Phenotype
Receptor, Serotonin, 5-HT2C
Receptors, Serotonin
Seizures

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9928241
DOI: 10.1111/j.1749-6632.1998.tb10175.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9928241-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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