Article
Sound-induced seizures in serotonin 5-HT2c receptor mutant mice.
Nature genetics - 1 Aug 1997
Brennan T J, Seeley W W, Kilgard M, Schreiner C E, Tecott L H
Abstract excerpt
The epilepsies are a heterogeneous collection of seizure disorders with a lifetime expectancy risk rate of 2-4%. A convergence of evidence indicates that heritable factors contribute significantly to seizure susceptibility. Genetically epilepsy-prone rodent strains have been frequently used to examine the effect of genetic factors on seizure susceptibility. The most extensively studied of these have been strains...
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