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Article

An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae.

Genetics - 1 Feb 1999

Smith J, Rothstein R

Abstract excerpt

An allele of RFA1, the largest subunit of the single-stranded DNA-binding complex RP-A, was identified as a suppressor of decreased direct-repeat recombination in rad1 rad52 double mutants. In this study, we used two LEU2 direct-repeat assays to investigate the mechanism by which the rfa1-D228Y allele increases recombination. We found that both intrachromatid and sister chromatid recombination are stimulated in...

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Identifiers

PMID: 9927442
DOI: 10.1093/genetics/151.2.447
PMCID: PMC1460496

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae.PMID 9927442Read ↗

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