An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae.

doi:10.1093/genetics/151.2.447

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Article

An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae.

Genetics - 1 Feb 1999

Smith J, Rothstein R

Abstract excerpt

An allele of RFA1, the largest subunit of the single-stranded DNA-binding complex RP-A, was identified as a suppressor of decreased direct-repeat recombination in rad1 rad52 double mutants. In this study, we used two LEU2 direct-repeat assays to investigate the mechanism by which the rfa1-D228Y a...

Topics

DNA Repair
DNA, Fungal
DNA-Binding Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Mutation
Rad52 DNA Repair and Recombination Protein
Recombination, Genetic
Replication Protein A
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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