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Article

Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break.

Molecular and cellular biology - 1 Dec 2003

Lee Sang Eun, Pellicioli Achille, Vaze Moreshwar B, Sugawara Neal, Malkova Anna, Foiani Marco, Haber James E

Abstract excerpt

Saccharomyces cells with a single unrepaired double-strand break adapt after checkpoint-mediated G(2)/M arrest. We have found that both Rad51 and Rad52 recombination proteins play key roles in adaptation. Cells lacking Rad51p fail to adapt, but deleting RAD52 suppresses rad51Delta. rad52Delta als...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Fungal

Share to DNA, Single-Stranded

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Share to Rad52 DNA Repair and Recombination Protein

Source

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Identifiers

PMID: 14612428
DOI: 10.1128/MCB.23.23.8913-8923.2003
PMCID: PMC262690

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14612428-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break.PMID 14612428Read ↗

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