Article
GSTT1-null genotype is a protective factor against bladder cancer.
Urology - 1 Nov 2002
Kim Wun-Jae, Kim Heon, Kim Cheol-Hwan, Lee Moo-Song, Oh Bong Ryoul, Lee Hyun Moo, Katoh Takahiko
Abstract excerpt
OBJECTIVES: To investigate the effects of homozygous deletions of GSTM1 and GSTT1 and smoking on bladder cancer, we conducted a case-control and ecological study. METHODS: The case group consisted of 216 patients with bladder cancer and the control group of 449 healthy Koreans. Every subject was personally interviewed to obtain a detailed smoking history, and a multiplex polymerase chain reaction method was used...
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