Article
Investigation of glutathione S-transferase M1 and T1 deletions in lung cancer.
Molecular biology reports - 1 Jan 2010
Altinisik Julide, Balta Zinnet B, Aydin Gunay, Ulutin Turgut, Buyru Nur
Abstract excerpt
Glutathione S-transferases (GSTs) M1 and T1 are known to be polymorphic in humans. Both polymorphisms are due to gene deletions which are responsible for the existence of null genotypes. Previous studies have suggested that GST genotypes may play a role in determining susceptibility to a number of unrelated cancers, including lung cancer. The GSTM1 and GSTT1 polymorphisms were determined by PCR-based analysis in...
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