Article
Enhanced hepatocyte growth factor expression associated with prolonged rat hepatic allograft survival in recipients pretreated with donor-specific blood.
Transplantation - 15 Jan 1999
Ichiguchi O, Yamaguchi Y, Miyanari N, Mori K, Yamada S, Yagi J, Hikiji K, Yokoyama Y, Ogawa M
Abstract excerpt
BACKGROUND: Pretransplantation injection of freshly heparinized donor blood (donor-specific blood transfusion, or DST) significantly prolongs the survival of hepatic allografts from ACI(RT1a) to LEW(RT1l) rats. We investigated hepatocyte growth factor (HGF) expression in rat hepatic allografts of recipients pretreated with or without DST. METHODS: The levels of HGF mRNA and protein in hepatic allografts were...
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