Article
Deleted form of hepatocyte growth factor ameliorates the mortality rate of severe thermal injury in rats.
Surgery - 1 Nov 1999
Arisawa H, Yamashita Y, Ogawa H, Masunaga H, Higashio K
Abstract excerpt
BACKGROUND: The modulating effects of the deleted form of hepatocyte growth factor (dHGF) on burn-induced mortality rates and hepatic protein synthesis were studied in rats. METHODS: Rats were anesthetized, subjected to a 40% full-thickness scald burn, and divided into 2 groups receiving dHGF and vehicle. RESULTS: In normal rats, dHGF-treatment (1 mg/kg intravenously, twice daily) for 5 days increased the...
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