Article
The time course of cell-mediated lympholysis in rat hepatic allograft recipients pretreated with a single donor-specific blood transfusion.
Transplantation - 1 Sept 1992
Katsumori T, Yamaguchi Y, Mori K, Makino Y, Misumi M, Takata N, Goto M, Kikuchi N, Ogawa M
Abstract excerpt
A single intravenous injection of 1 ml freshly heparinized donor blood seven days before transplantation significantly prolonged the survival of subsequent donor-specific hepatic allografts in the fully allogeneic ACI(RT1a-to-LEW(RT1l)) rat combination. The time course of cell-mediated lympholysis was studied in this animal model. The activity of CML in lymphocytes infiltrating into the hepatic allograft (CML-G)...
Topics
- Animals
- Blood Transfusion
- Cytotoxicity Tests, Immunologic
- Cytotoxicity, Immunologic
- Graft Survival
- Liver
- Liver Transplantation
- Male
- Mitotic Index
- Phenotype
- Rats