Article
Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation.
Transplantation - 15 Sept 1998
Hayamizu K, Zeng D, Huie P, Garcia-Ojeda M E, Bloch D A, Fong L, Engleman E G, Sibley R K, Strober S
Abstract excerpt
BACKGROUND: Previous studies showed that a combination of posttransplant total lymphoid irradiation (TLI), rabbit antithymocyte globulin (ATG), and a single donor blood transfusion induced tolerance to ACI heart allografts in Lewis rats. All three modalities were required to achieve tolerance. The objective of the current study was to determine the subset(s) of cells in the donor blood that facilitated long-term...
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