Article
Variant antibody identification by peptide mapping.
Biotechnology and bioengineering - 20 Feb 1999
Wan M, Shiau F Y, Gordon W, Wang G Y
Abstract excerpt
During development of CGP56901, a monoclonal antibody (MAb) specific for a unique epitope on human IgE, the protein A-purified IgG from one of the candidate production cell lines, showed an additional minor heavy chain (H-chain) band with a molecular weight slightly lower than that of the principal H-chain band on SDS-PAGE. The N-terminal amino acid sequence of this minor H-chain species indicated that at least...
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