Variant antibody identification by peptide mapping.

doi:10.1002/(sici)1097-0290(19990220)62:4<485::aid-bit12>3.0.co;2-e

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Article

Variant antibody identification by peptide mapping.

Biotechnology and bioengineering - 20 Feb 1999

Wan M, Shiau F Y, Gordon W, Wang G Y

Abstract excerpt

During development of CGP56901, a monoclonal antibody (MAb) specific for a unique epitope on human IgE, the protein A-purified IgG from one of the candidate production cell lines, showed an additional minor heavy chain (H-chain) band with a molecular weight slightly lower than that of the princip...

Topics

Amino Acid Sequence
Antibodies, Monoclonal
Base Sequence
Biotechnology
Crossing Over, Genetic
DNA, Complementary
Genetic Variation
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Models, Genetic
Peptide Mapping

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