Article
Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties.
Molecular immunology - 1 Dec 1999
Lavoie T B, Mohan S, Lipschultz C A, Grivel J C, Li Y, Mainhart C R, Kam-Morgan L N, Drohan W N, Smith-Gill S J
Abstract excerpt
The mAbs HyHEL-8, HyHEL-26 (HH8, and HH26, respectively) recognize epitopes on hen egg-white lysozyme (HEL) highly overlapping with the structurally defined HH10 epitope, while the structurally related XRPC-25 is specific for DNP and does not bind HEL. All four Abs appear to use the same Vk23 ger...
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