Article
The T0 domain of rabbit KV1.3 regulates steady state channel protein level.
Biochemical and biophysical research communications - 8 Jan 1999
Segal A S, Yao X, Desir G V
Abstract excerpt
The Shaker superfamily encodes voltage-gated potassium (Kv) channels. The amino (N) terminus is important for channel assembly and mediates fast inactivation. We recently isolated a Kv channel from rabbit kidney, denoted rabKv1.3 (Yao et al., J. Clin. Invest. 97, 2525-2533, 1996) and found that d...
Topics
- Animals
- Base Sequence
- Binding Sites
- Ion Channel Gating
- Kidney
- Molecular Sequence Data
- Mutation
- Patch-Clamp Techniques
- Potassium Channels
- Rabbits
- Shaker Superfamily of Potassium Channels
- Structure-Activity Relationship