Article
Atypical phenotypes from flatworm Kv3 channels.
Journal of neurophysiology - 1 May 2006
Klassen Tara L, Buckingham Steven D, Atherton Donna M, Dacks Joel B, Gallin Warren J, Spencer Andrew N
Abstract excerpt
Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radiation provides a comprehensive sampling of sequence space that is necessary to develop generally...
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