Article
Chromosomal linkage analysis of porphyria in mice induced by hexachlorobenzene-iron synergism: a model of sporadic porphyria cutanea tarda.
Pharmacogenetics - 1 Dec 1998
Akhtar R A, Smith A G
Abstract excerpt
Genetic susceptibility to toxic chemicals is of major importance but most studies concentrate on candidate genes and searches for unknown susceptibility genes are uncommon. Human sporadic porphyria cutanea tarda is usually precipitated by alcohol, oestrogens, hepatitis viruses, HIV or haemodialys...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- DNA Primers
- Drug Synergism
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Hexachlorobenzene
- Iron
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Porphyria Cutanea Tarda
- Species Specificity
- Uroporphyrins