Article
Iron overload in porphyria cutanea tarda.
Haematologica - 1 Mar 1999
Sampietro M, Fiorelli G, Fargion S
Abstract excerpt
BACKGROUND AND OBJECTIVE: Porphyria cutanea tarda (PCT) is a disorder of porphyrin metabolism associated with decreased activity of uroporphyrinogen decarboxylase (URO-D) in the liver. The relevance of iron in the pathogenesis of PCT is well established: iron overload is one of the factors that trigger the clinical manifestations of the disease and iron depletion remains the cornerstone of therapy for PCT. A role...
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