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Article

Three molecular determinants of malignant conversion and their potential as therapeutic targets.

Current opinion in oncology - 1 Jan 1999

Dome J S, Look A T

Abstract excerpt

The past decade has been marked by an explosion of knowledge regarding the dysregulation of cancer at the molecular level. It has become apparent that oncogenes, tumor suppressor genes, and other ancillary molecules interact in complex pathways that govern cellular homeostasis. We review three molecular events that have been implicated in tumorigenesis and define pathways ripe for the development of new...

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PMID: 9914880
DOI: 10.1097/00001622-199901000-00013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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