Article
Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.
Development (Cambridge, England) - 1 Feb 1999
Frade J M, Barde Y A
Abstract excerpt
The role of nerve growth factor (NGF) and of the neurotrophin receptor p75 (p75(NTR)) in programmed cell death was investigated in the retina and the spinal cord of mouse embryos. Large numbers of cells express p75(NTR) in and along the developing optic nerve and in the mantle zone of the spinal...
Topics
- Animals
- Apoptosis
- Gene Expression Regulation, Developmental
- Genotype
- Immunohistochemistry
- In Situ Nick-End Labeling
- Mice
- Mutation
- Nerve Growth Factors
- Phenotype
- Receptor, Nerve Growth Factor
- Receptors, Nerve Growth Factor
- Retina
- Spinal Cord