Article
Thymine metabolism and thymineless death in prokaryotes and eukaryotes.
Annual review of microbiology - 1 Jan 1998
Ahmad S I, Kirk S H, Eisenstark A
Abstract excerpt
For many years it has been known that thymine auxotrophic microorganisms undergo cell death in response to thymine starvation [thymineless death (TLD)]. This effect is unusual in that deprivation of many other nutritional requirements has a biostatic, but not lethal, effect. Studies of numerous microbes have indicated that thymine starvation has both direct and indirect effects. The direct effects involve both...
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