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Article

Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.

Molecular and cellular biology - 1 Feb 1999

Kondo T, Matsumoto K, Sugimoto K

Abstract excerpt

Genetic analysis has suggested that RAD17, RAD24, MEC3, and DDC1 play similar roles in the DNA damage checkpoint control in budding yeast. These genes are required for DNA damage-induced Rad53 phosphorylation and considered to function upstream of RAD53 in the DNA damage checkpoint pathway. Here we identify Mec3 as a protein that associates with Rad17 in a two-hybrid screen and demonstrate that Rad17 and Mec3...

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Identifiers

PMID: 9891048
DOI: 10.1128/MCB.19.2.1136
PMCID: PMC116043

Genes

RAD17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.PMID 9891048Read ↗

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Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae.Semantic proximity Read ↗

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