Complementation of defective colony-stimulating factor 1 receptor signaling and mitogenesis by Raf and v-Src.

doi:10.1128/MCB.19.2.1101

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Article

Complementation of defective colony-stimulating factor 1 receptor signaling and mitogenesis by Raf and v-Src.

Molecular and cellular biology - 1 Feb 1999

Aziz N, Cherwinski H, McMahon M

Abstract excerpt

Ras-activated signal transduction pathways are implicated in the control of cell proliferation, differentiation, apoptosis, and tumorigenesis, but the molecular mechanisms mediating these diverse functions have yet to be fully elucidated. Conditionally active forms of Raf, v-Src, and MEK1 were us...

Topics

3T3 Cells
Animals
Cell Division
Cyclin D1
Enzyme Activation
Gene Expression Regulation
Genes, src
Genetic Complementation Test
Humans
MAP Kinase Kinase 1
Mice
Mitogen-Activated Protein Kinase Kinases
Mutation
Ornithine Decarboxylase
Protein Serine-Threonine Kinases
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-myc
Proto-Oncogene Proteins c-raf

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Identifiers

PMID: 9891045
DOI: 10.1128/MCB.19.2.1101
PMCID: PMC116040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9891045-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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