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Article

Nuclear factors and type 2 diabetes.

Schweizerische medizinische Wochenschrift - 5 Dec 1998

Froguel P

Abstract excerpt

Recent studies have shown that mutations in four transcription factors, hepatocyte nuclear factor-4 alpha (HNF-4 alpha), hepatocyte nuclear factor-1 alpha (HNF-1 alpha), hepatocyte nuclear factor-1 beta (HNF-1 beta), and insulin promoter factor-1 (IPF-1), are responsible for maturity onset diabetes of the young (MODY) which is characterised by an early age of onset and autosomal dominant inheritance. MODY is not...

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Source

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PMID: 9887471

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear factors and type 2 diabetes.PMID 9887471Read ↗

Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences.Semantic proximity Read ↗

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.Semantic proximity Read ↗

[Mutations in the genes of the HNF-family cause maturity-onset diabetes of the young (MODY)].Semantic proximity Read ↗

HNF-4alpha: from MODY to late-onset type 2 diabetes.Semantic proximity Read ↗

The role of transcription factors in maturity-onset diabetes of the young.Semantic proximity Read ↗

Molecular etiologies of MODY and other early-onset forms of diabetes.Semantic proximity Read ↗

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)Semantic proximity Read ↗

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)Semantic proximity Read ↗

Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia.Semantic proximity Read ↗

Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway.Semantic proximity Read ↗

Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).Semantic proximity Read ↗

Association of novel variants in the hepatocyte nuclear factor 4A gene with maturity onset diabetes of the young and early onset type 2 diabetes.Semantic proximity Read ↗

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