Nuclear factors and type 2 diabetes.

Article

Nuclear factors and type 2 diabetes.

Schweizerische medizinische Wochenschrift - 5 Dec 1998

Froguel P

Abstract excerpt

Recent studies have shown that mutations in four transcription factors, hepatocyte nuclear factor-4 alpha (HNF-4 alpha), hepatocyte nuclear factor-1 alpha (HNF-1 alpha), hepatocyte nuclear factor-1 beta (HNF-1 beta), and insulin promoter factor-1 (IPF-1), are responsible for maturity onset diabet...

Topics

Adult
Chromosome Aberrations
Chromosome Disorders
Chromosome Mapping
Diabetes Mellitus, Type 2
Genes, Dominant
Genetic Predisposition to Disease
Humans
Hyperglycemia
Transcription Factors

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