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Article

[Mutations in the genes of the HNF-family cause maturity-onset diabetes of the young (MODY)].

Nihon rinsho. Japanese journal of clinical medicine - 1 Sept 1998

Takeda J

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a monogenic form of non-insulin-dependent diabetes mellitus (NIDDM) characterized by an early age of onset, often in childhood or adolescence and usually < 25 years of age, and autosomal dominant inheritance. Clinical characterization of patients with MODY indicates that impaired insulin secretion is the primary defect responsible for the hyperglycemia in these...

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PMID: 9780731

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[Mutations in the genes of the HNF-family cause maturity-onset diabetes of the young (MODY)].PMID 9780731Read ↗

[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics].Semantic proximity Read ↗

Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young.Semantic proximity Read ↗

Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences.Semantic proximity Read ↗

Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia.Semantic proximity Read ↗

Molecular etiologies of MODY and other early-onset forms of diabetes.Semantic proximity Read ↗

Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young.Semantic proximity Read ↗

The role of transcription factors in maturity-onset diabetes of the young.Semantic proximity Read ↗

Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY).Semantic proximity Read ↗

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)Semantic proximity Read ↗

Regulation of pancreatic beta-cell function by the HNF transcription network: lessons from maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization.Semantic proximity Read ↗

Maturity-onset diabetes of the young (MODY): a new challenge for pediatric diabetologists.Semantic proximity Read ↗

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