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Article

The role of transcription factors in maturity-onset diabetes of the young.

Molecular genetics and metabolism - 1 Jan 2000

Mitchell Simon M S, Frayling Timothy M

Abstract excerpt

The study of maturity-onset diabetes of the young (MODY), an autosomal dominant form of early-onset diabetes mellitus characterised by defective insulin secretion has been extremely successful in two ways. Firstly it has enabled definitive diagnosis for patients. This allows more accurate prediction of disease and treatment requirements. Secondly it has facilitated an increased understanding of the genes and...

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Identifiers

PMID: 12359128
DOI: 10.1016/s1096-7192(02)00150-6

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NEUROD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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The role of transcription factors in maturity-onset diabetes of the young.PMID 12359128Read ↗

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Regulation of pancreatic beta-cell function by the HNF transcription network: lessons from maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)Semantic proximity Read ↗

Maturity-onset diabetes of the young (MODY): a new challenge for pediatric diabetologists.Semantic proximity Read ↗

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)Semantic proximity Read ↗

Experimental models of transcription factor-associated maturity-onset diabetes of the young.Semantic proximity Read ↗

[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics].Semantic proximity Read ↗

HNF-4alpha: from MODY to late-onset type 2 diabetes.Semantic proximity Read ↗

Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia.Semantic proximity Read ↗

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism.Semantic proximity Read ↗

Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization.Semantic proximity Read ↗

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