Article
Prothrombin antigen levels in symptomatic and asymptomatic carriers of the 20210A prothrombin variant.
British journal of haematology - 1 Dec 1998
Simioni P, Tormene D, Manfrin D, Gavasso S, Luni S, Stocco D, Girolami A
Abstract excerpt
A recently discovered variant in the prothrombin gene (20210A) has been found in approximately 5-10% of patients with venous thromboembolism. It has been shown that patients with this variant present with high levels of prothrombin in plasma and this is maintained to be the most likely mechanism by which the risk of thrombosis is increased. We have evaluated prothrombin antigen levels in 50 carriers of the 20210A...
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