Prothrombin antigen levels in symptomatic and asymptomatic carriers of the 20210A prothrombin variant.

doi:10.1046/j.1365-2141.1998.01112.x

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Article

Prothrombin antigen levels in symptomatic and asymptomatic carriers of the 20210A prothrombin variant.

British journal of haematology - 1 Dec 1998

Simioni P, Tormene D, Manfrin D, Gavasso S, Luni S, Stocco D, Girolami A

Abstract excerpt

A recently discovered variant in the prothrombin gene (20210A) has been found in approximately 5-10% of patients with venous thromboembolism. It has been shown that patients with this variant present with high levels of prothrombin in plasma and this is maintained to be the most likely mechanism...

Topics

Adult
Antigens
Enzyme-Linked Immunosorbent Assay
Factor V
Female
Heterozygote
Humans
Male
Middle Aged
Mutation
Prothrombin
Thrombophilia

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