Article
Prothrombin activity and concentration in healthy subjects with and without the prothrombin G20210A mutation.
Thrombosis research - 15 Sept 2000
von Ahsen N, Lewczuk P, Schütz E, Oellerich M, Ehrenreich H
Abstract excerpt
A common mutation in the prothrombin gene (G20210A) is associated with elevated prothrombin levels and thrombosis. The pathomechanism related to the G20210A mutation is currently not understood and the interdependence of prothrombin activity and prothrombin concentration in plasma is still poorly defined. Six of 191 blood donors examined in the present study carried the prothrombin allele G20210A. Despite the...
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