Circulating activated protein C in subjects with heterozygous Gln506-factor V.

doi:10.1159/000022381

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Article

Circulating activated protein C in subjects with heterozygous Gln506-factor V.

Haemostasis - 1 Jan 2000

Petäjä J, Hakala L, Rasi V, Griffin J H

Abstract excerpt

Congenital resistance to activated protein C due to a point mutation in the factor V gene (Gln506-FV) is the most common genetic risk factor for familial venous thrombosis. Considering the central role of activated protein C as a physiological anticoagulant, the question of why the thrombotic ris...

Topics

Adolescent
Adult
Aged
Enzyme Activation
Factor V
Female
Genetic Carrier Screening
Glutamine
Humans
Male
Middle Aged
Mutation
Protein C

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