Article
Incidence of activated protein C resistance caused by the ARG 506 GLN mutation in factor V in 113 unrelated symptomatic protein C-deficient patients. The French Network on the behalf of INSERM.
Blood - 1 Jul 1995
Gandrille S, Greengard J S, Alhenc-Gelas M, Juhan-Vague I, Abgrall J F, Jude B, Griffin J H, Aiach M
Abstract excerpt
Because multiple risk factors in one patient may increase the clinical expression of thrombophilia, we assessed the presence in protein C-deficient patients of the factor V Arg 506 Gln mutation responsible for activated protein C resistance. Using a strategy allowing rapid screening of factor V e...
Topics
- Adolescent
- Alleles
- Base Sequence
- Child
- Child, Preschool
- Codon
- Factor V
- Factor V Deficiency
- Female
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Point Mutation
- Protein C
- Retrospective Studies