Article
Activated protein C resistance--a major risk factor for thrombosis.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies - 1 Jul 1997
Rosén S B, Sturk A
Abstract excerpt
Resistance to activated protein C is a recently detected phenomenon that has gained a rapid acceptance as a major risk factor for venous thromboembolism. The phenotypic expression of resistance to activated protein C is characterized by a poor response to the anticoagulant activity of activated p...
Topics
- Antiphospholipid Syndrome
- Blood Coagulation
- Contraceptives, Oral
- Drug Resistance
- Enzyme Activation
- Factor V
- Female
- Homocystinuria
- Humans
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Postoperative Complications
- Pregnancy
- Protein C
- Thromboembolism
- Thrombophlebitis
- Thrombosis
