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Article

Normalized activated protein C ratio itself not associated with increased risk of venous thromboembolism.

Contraception - 1 Nov 1998

Heinemann L A, Assmann A, Spannagl M, Schramm W, Dick A, Kluft C, de Maat M P

Abstract excerpt

Recently, discussions focused on the question whether acquired activated (APC) resistance is a clue to the observed association between venous thromboembolism (VTE) risk and oral contraceptive (OC) use, especially with the so-called third-generation OC. The objective of our study was to check the validity of acquired APC resistance regarding VTE risk in a case-control study. Sixty-seven women with confirmed VTE...

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Source

Identifiers

PMID: 9883389
DOI: 10.1016/s0010-7824(98)00111-5

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Normalized activated protein C ratio itself not associated with increased risk of venous thromboembolism.PMID 9883389Read ↗

The phenomenon known as acquired activated protein C resistanceSemantic proximity Read ↗

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Hormone replacement therapy and acquired resistance to activated protein C: results of a randomized, double-blind, placebo-controlled trial.Semantic proximity Read ↗

Thrombin generation and activated protein C resistance in the absence of factor V Leiden correlates with the risk of recurrent venous thromboembolism in women aged 18-65 years.Semantic proximity Read ↗

Laboratory Testing for the Evaluation of Phenotypic Activated Protein C Resistance.Semantic proximity Read ↗

Low level of circulating activated protein C is a risk factor for venous thromboembolism.Semantic proximity Read ↗

Influence of factor VIII/von Willebrand complex on the activated protein C-resistance phenotype and on the risk for venous thromboembolism in heterozygous carriers of the factor V Leiden mutation.Semantic proximity Read ↗

Activated protein C resistance: the most common risk factor for venous thromboembolism.Semantic proximity Read ↗

Comparison of three activated protein C resistance tests in the risk assessment of venous thrombosis in non-carriers of the factor V Leiden mutation.Semantic proximity Read ↗

Inherited resistance to activated protein C, a major cause of venous thrombosis, is due to a mutation in the factor V gene.Semantic proximity Read ↗

Congenital and acquired activated protein C resistance.Semantic proximity Read ↗

Prevalence of activated protein C resistance and analysis of clinical profile in thromboembolic patients. A Belgian prospective study.Semantic proximity Read ↗

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