Analysis of a vaccinia virus mutant expressing a nonpalmitylated form of p37, a mediator of virion envelopment.

doi:10.1128/JVI.72.6.5108-5120.1998

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Article

Analysis of a vaccinia virus mutant expressing a nonpalmitylated form of p37, a mediator of virion envelopment.

Journal of virology - 1 Jun 1998

Grosenbach D W, Hruby D E

Abstract excerpt

Vaccinia virus encodes a 37-kDa palmitylated protein (p37) that is required for envelopment, translocation, and cell-to-cell spread of virions. We have analyzed the biological significance of the palmitate modification by constructing a recombinant vaccinia virus that expresses a nonpalmitylated...

Topics

Animals
Cell Line
DNA, Recombinant
DNA, Viral
Membrane Proteins
Mutation
Recombination, Genetic
Vaccinia virus
Viral Envelope Proteins
Virion
Virus Replication

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