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Article

Mutations in both the structured domain and N-terminus of histone H2B bypass the requirement for Swi-Snf in yeast.

The EMBO journal - 4 Jan 1999

Recht J, Osley M A

Abstract excerpt

The chromatin elements targeted by the ATPdependent, Swi-Snf nucleosome-remodeling complex are unknown. To address this question, we generated mutations in yeast histone H2B that suppress phenotypes associated with the absence of Swi-Snf. Sin- (Swi-Snf-independent) mutations occur in residues involved in H2A-H2B dimer formation, dimer- tetramer association, and in the H2B N-terminus. The strongest and most...

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Identifiers

PMID: 9878065
DOI: 10.1093/emboj/18.1.229
PMCID: PMC1171117

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