Article
Mutations in both the structured domain and N-terminus of histone H2B bypass the requirement for Swi-Snf in yeast.
The EMBO journal - 4 Jan 1999
Recht J, Osley M A
Abstract excerpt
The chromatin elements targeted by the ATPdependent, Swi-Snf nucleosome-remodeling complex are unknown. To address this question, we generated mutations in yeast histone H2B that suppress phenotypes associated with the absence of Swi-Snf. Sin- (Swi-Snf-independent) mutations occur in residues inv...
Topics
- Amino Acid Sequence
- Chromatin
- Chromosomal Proteins, Non-Histone
- DNA-Binding Proteins
- Dimerization
- Fungal Proteins
- Genes, Fungal
- Glycoside Hydrolases
- Histone Acetyltransferases
- Histones
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Nucleosomes
- Phenotype
- Protein Conformation
- Protein Kinases
- Protein Structure, Secondary