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Article

Heterogeneous point mutations of the p53 gene in pulmonary fibrosis

1 Dec 1998

Abstract excerpt

Lung cancer is a frequent complication in pulmonary fibrosis. Overexpression of p53 proteins has been demonstrated by immunostaining in bronchoepithelial cells in patients with idiopathic pulmonary fibrosis. However, it is still unclear whether this overexpressed p53 protein is wild-type or mutant. It was hypothesized that pulmonary fibrosis may be a precancerous lesion with deoxyribonucleic acid point mutations...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Identifiers

PMID: 9877499
DOI: 10.1183/09031936.98.12061404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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