Article
Variations in HIV-1 pol gene associated with reduced sensitivity to antiretroviral drugs in treatment-naive patients.
AIDS (London, England) - 24 Dec 1998
Birk M, Sönnerborg A
Abstract excerpt
OBJECTIVE: Various drugs against the HIV-1 enzymes reverse transcriptase (RT) and protease have been introduced in the last few years: protease inhibitors, nucleoside RT inhibitors (NRTI) and non-NRTI (NNRTI). Several sequence variations associated with reduced drug sensitivity have been described in the HIV-1 pol gene. DESIGN: To analyse the occurrence of mutations associated with drug resistance in...
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