Article
Low prevalence of primary mutations associated with drug resistance in antiviral-naive patients at therapy initiation.
AIDS (London, England) - 8 Mar 2002
Perno Carlo Federico, Cozzi-Lepri Alessandro, Balotta Claudia, Bertoli Ada, Violin Michela, Monno Laura, Zauli Tiziano, Montroni Maria, Ippolito Giuseppe, d'Arminio-Monforte Antonella
Abstract excerpt
OBJECTIVE: To assess the prevalence of mutations in the reverse-transcriptase (RT) and protease (PR) region in a cohort of chronically-infected HIV-positive patients requiring highly active antiretroviral therapy (HAART). METHODS: The study included 347 patients enrolled in the Italian Cohort of Antiretroviral Naive patients (I.CO.NA) who had to initiate HAART. The whole PR-region, and amino acids 1-320 of...
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