Article
Retrospective analysis of the HIV-1 reverse transcriptase inhibitors' resistance in Silesia, Poland.
Medical science monitor : international medical journal of experimental and clinical research - 1 Feb 2011
Smolén Joanna, Kruszyński Piotr, Bratosiewicz-Wąsik Jolanta, Witor Adam, Wąsik Tomasz J
Abstract excerpt
BACKGROUND: This study was a retrospective analysis of drug resistance mutations among HIV-1 strains prevalent in Silesia, Poland, from the origin of the epidemic to 2004. The investigations included both type and frequency of the reverse transcriptase inhibitors' resistance mutations and estimation of the drugs' resistance levels. MATERIAL/METHODS: Proviral DNA, obtained from peripheral blood mononuclear cells...
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