Article
Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study.
AIDS (London, England) - 4 Feb 1999
Lorenzi P, Opravil M, Hirschel B, Chave J P, Furrer H J, Sax H, Perneger T V, Perrin L, Kaiser L, Yerly S
Abstract excerpt
OBJECTIVE: To assess the prognostic significance of drug-associated mutations in the protease and reverse transcriptase (RT) genes on virological response to salvage therapy. PATIENTS: All patients from four centres of the Swiss HIV Cohort Study who were switched, between February and October 1997, to nelfinavir plus other antiretroviral drugs following failure of highly active antiretroviral therapy (HIV-1 RNA...
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