Resistance mechanism of Acinetobacter spp. strains resistant to DW-116, a new quinolone.

doi:10.1007/BF02975293

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Article

Resistance mechanism of Acinetobacter spp. strains resistant to DW-116, a new quinolone.

Archives of pharmacal research - 1 Jun 1998

Choi K H, Baek M C, Kim B K, Choi E C

Abstract excerpt

DW-116 is a new fluoroquinolone antimicrobial agent with a broad spectrum. In order to elucidate the resistance mechanism to DW-116 in Acinetobacter spp. bacteria, total chromosomal DNA was isolated from 10 strains of Acinetobacter spp. resistant to DW-116. Quinolone resistance determinant region...

Topics

Acinetobacter
Acinetobacter Infections
Anti-Infective Agents
Base Sequence
Electrophoresis, Polyacrylamide Gel
Fluoroquinolones
Microbial Sensitivity Tests
Molecular Sequence Data
Mutation
Piperazines
Polymerase Chain Reaction
Quinolones
Topoisomerase II Inhibitors

Source

Open in PubMed

Identifiers

PMID: 9875449
DOI: 10.1007/BF02975293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9875449-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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