Article
Molecular analysis of fluoroquinolone-resistance in Escherichia coli on the aspect of gyrase and multiple antibiotic resistance (mar) genes.
Yonsei medical journal - 1 Dec 1998
Park Y H, Yoo J H, Huh D H, Cho Y K, Choi J H, Shin W S
Abstract excerpt
We analyzed the fluoroquinolone resistance mechanism of 28 isolates of ciprofloxacin-resistant E. coli from patients who received ciprofloxacin as a regimen of a selective gut decontamination. Isolates distinctive by infrequent restriction site polymerase chain reaction (IRS-PCR) were subjected to Hinf I restriction fragment length polymorphism analysis, single-stranded conformation polymorphism (SSCP), and...
Topics
- Ciprofloxacin
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Escherichia coli
- Humans
- Mutation
