Article
No difference in stem cell somatic mutation between the background mucosa of right- and left-sided sporadic colorectal carcinomas.
The Journal of pathology - 1 Sept 1998
Campbell F, Appleton M A, Shields C J, Williams G T
Abstract excerpt
Epidemiological, morphological, and molecular differences exist between carcinomas of the right and left sides of the large bowel. To investigate whether this is reflected in differences in somatic mutation frequency in the background mucosa, mutation of the neutral O-acetyltransferase gene (oat)...
Topics
- Acetyltransferases
- Aged
- Aged, 80 and over
- Colonic Neoplasms
- Female
- Humans
- Intestinal Mucosa
- Male
- Middle Aged
- Mutation
- Neoplastic Stem Cells
- Prospective Studies