Changes in keratin and filaggrin expression in the skin of chronic proliferative dermatitis (cpdm) mutant mice.

doi:10.1159/000028050

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Article

Changes in keratin and filaggrin expression in the skin of chronic proliferative dermatitis (cpdm) mutant mice.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1999

HogenEsch H, Boggess D, Sundberg J P

Abstract excerpt

The expression of keratins and filaggrin by keratinocytes is a highly regulated process and depends on their state of differentiation and proliferation. As such, these proteins can be used as markers to determine if keratinocyte differentiation is normal. Mutant cpdm/cpdm mice develop a chronic s...

Topics

Animals
Chronic Disease
Dermatitis
Filaggrin Proteins
Hyperplasia
Immunohistochemistry
Intermediate Filament Proteins
Keratinocytes
Keratins
Mice
Mice, Inbred C57BL
Mutation
Skin

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