Article
Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm).
The American journal of pathology - 1 Mar 1996
Gijbels M J, Zurcher C, Kraal G, Elliott G R, HogenEsch H, Schijff G, Savelkoul H F, Bruijnzeel P L
Abstract excerpt
Chronic proliferative dermatitis is a spontaneous mutation in C57BL/Ka mice (cpdm/cpdm), showing alopecia, epithelial hyperproliferation, infiltration by eosinophils and macrophages, and vascular dilatation. To further elucidate its pathogenesis, organs of 1-, 2-, 3-, 4-, 5-, and 6-week-old cpdm/cpdm mice were examined. At 4 weeks, the epidermal thickness was increased, whereas already at 3 weeks, the...
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